This dataset covers the entire China Pakistan Economic Corridor region with a spatial resolution of 0.25 ° × 0.25 °, with a time span from January 1, 1961 to December 31, 2015. Based on the daily minimum temperature data of 65 meteorological stations in the China Pakistan Economic Corridor and its surrounding areas, using DEM data from the region as covariates, ANUSPLIN software was used for spatial interpolation. Taking the data from other meteorological stations in the research area that have not been interpolated as a reference, combined with the commonly used daily minimum temperature dataset in the international community, the validation shows that this dataset has higher accuracy and can better reflect the true spatiotemporal distribution characteristics of the lowest temperature in the China Pakistan Economic Corridor. The data volume is 171MB, approximately 20000 pieces.